Advances in the clinicopathology and molecular genetic changes of papillary breast tumors
10.13315/j.cnki.cjcep.2025.03.016
- VernacularTitle:乳腺乳头状肿瘤临床病理及分子遗传学研究进展
- Author:
Zhihui HOU
1
;
Li LI
Author Information
1. 山东大学齐鲁医院病理科,济南 250012
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
papillary tumors;
pathological features;
molecular characteristics;
literature review
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(3):374-379
- CountryChina
- Language:Chinese
-
Abstract:
Papillary neoplasms of breast are a group of heterogenous tumors characterized by epithelial hyperplasia and the formation of papillary structures containing fibrovascular axes.Their overlapping morphological and immuno-phenotypes pose a major challenge to pathological diagnosis,so the diagnosis and prognosis of papillary tumors have been the focus of debate.Furthermore,the use of molecular assays has revealed the genetic heterogeneity of the histo-logical subtypes and identified unique molecular variant features in each subtype.This article reviews the molecular ge-netic developments and clinicopathological characteristics of papillary breast tumors.
