Research progress on targeted drug delivery strategies in inflammato-ry lung diseases
10.12092/j.issn.1009-2501.2025.03.003
- VernacularTitle:靶向递送策略在炎症性肺部疾病中的研究进展
- Author:
Xiaonan LI
1
;
Yang LI
1
;
Zhangxi XU
1
;
Shuzhen KANG
1
;
Li KONG
1
;
Zhiping ZHANG
1
Author Information
1. 华中科技大学同济医学院药学院,武汉 430030,湖北
- Publication Type:Journal Article
- Keywords:
inflammatory diseases;
pulmonary disease;
targeted delivery;
nanomedicine
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(3):313-324
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory lung diseases are cur-rently a major challenge threatening human health and life.Imbalanced inflammation and excessive in-flammation can lead to tissue damage and trigger the occurrence and development of systemic dis-eases.Anti-inflammatory treatment is of vital im-portance for improving patient survival and quality of life.In recent years,significant progress has been made in the exploration and research of drug targeting strategies,effectively addressing issues such as slow onset,low bioavailability,and rapid in vivo clearance rates during drug delivery.Drug tar-geting can increase local drug concentrations,re-duce dosing frequency,and mitigate side effects.This review primarily elaborates on the classifica-tion and characteristics of inflammatory lung dis-eases.It comprehensively reviews targeted drug de-livery strategies for inflammatory lung diseases from three perspectives:local targeting,passive tar-geting,and active targeting.Furthermore,it dis-cusses the prospects and challenges of drug target-ed therapy for lung diseases,potentially providing new research and application ideas for the target-ed treatment of inflammatory lung diseases.
