Bilateral choroidal detachment induced by topiramate
- VernacularTitle:托吡酯致双眼脉络膜脱离
- Author:
Zhenhuan ZHAO
1
;
Lei LI
1
;
Yu LIANG
1
;
Lei FU
1
;
Fanbo JING
1
;
Haijun QU
1
Author Information
- Publication Type:Journal Article
- Keywords: Topiramate; Choroidal effusions; Epilepsy
- From: Adverse Drug Reactions Journal 2021;23(11):607-608
- CountryChina
- Language:Chinese
- Abstract: A 57-year-old male patient with epilepsy was additionally given topiramate 25 mg orally once at night because of poor curative effect of sodium valproate. Seven days later, the patient developed vision loss with eye pain and swelling. Ocular ultrasonography showed bilateral choroidal detachment, which was considered to be related to topiramate. Topiramate was discontinued and prednisone acetate 60 mg once daily was given, and 8 days later, the patient′s eye pain and swelling were improved. Ocular ultrasonography showed that choroidal detachment disappeared. Fifteen days after drug withdrawal, his ocular symptoms disappeared.
