The potential joint application of minimally invasive technology and tissue engineering to the treatment of retinal detachment
10.13389/j.cnki.rao.2025.0058
- VernacularTitle:微创技术和组织工程在视网膜脱离治疗中融合应用的潜力
- Author:
Zhongzhong XU
1
;
Moqi TIAN
;
Yuanyuan YAN
Author Information
1. 450046 河南省郑州市,河南中医药大学医学院;450000 河南省郑州市,河南中医药大学第五临床医学院(郑州人民医院)眼科
- Publication Type:Journal Article
- Keywords:
retinal detachment;
minimally invasive techniques;
tissue engineering;
biomaterials;
cell therapy
- From:
Recent Advances in Ophthalmology
2025;45(4):326-336
- CountryChina
- Language:Chinese
-
Abstract:
Retinal detachment(RD)is defined as a separation between the neuroepithelial layer and the pigment epi-thelial layer of the retina,which is a serious ophthalmologic emergency that,if left untreated,may lead to permanent vision loss.Thus,the study of its treatment is of great importance.Current treatments include laser photocoagulation,pneumatic retinal fixation,scleral buckling,and vitrectomy,etc.With the advancement of minimally invasive surgical techniques,minimally invasive vitrectomy has become an important treatment.The development of smaller-diameter instruments such as 23 G,25 G,and 27 G has helped reduce surgical trauma by decreasing the size of the surgical incision in minimally inva-sive surgeries,improving surgical safety and effectiveness.At the same time,tissue engineering has emerged as a promising technique in retinal repair,especially in the application of biomaterials and the research of cell therapy.Although research-ers have achieved promising results currently,there are still some challenges,such as the biocompatibility of biomaterials,the effectiveness of cell therapy,and the evaluation of long-term efficacy.Therefore,the purpose of this article is to review the current status of the application of minimally invasive techniques and tissue engineering in the treatment of retinal de-tachment,to discuss their potential advantages,limitations,and trends in their integration,and to look into the future di-rection of development to provide guidance for clinical practice.
