Hematuria induced by ketorolac tromethamine injection in a child
10.3760/cma.j.cn114015-20200203-00078
- VernacularTitle:酮咯酸氨丁三醇致幼儿血尿
- Author:
Yanlong QIU
1
;
Haifang GUAN
Author Information
1. 山东省平邑县人民医院药剂科,平邑 273300
- Publication Type:Journal Article
- Keywords:
Ketorolac tromethamine;
Hematuria;
Proteinuria;
Child, preschool
- From:
Adverse Drug Reactions Journal
2021;23(1):49-50
- CountryChina
- Language:Chinese
-
Abstract:
A 2-year-old boy with hydrocele of spermatic cord received an IV infusion of ketorolac tromethamine injection 7 mg after laparoscopic high ligation of bilateral sheath to relieve pain. About 17 hours after the medication, the boy developed gross hematuria. Ultrasonic examination showed blood clots in the bladder. Routine urine analysis showed urine occult blood (++), red blood cells >50 cells per high-power field in urine microscopy, and protein (+++). The boy did not use other drugs in the same period, and hematuria related to ketorolac tromethamine injection was considered. The boy received IV infusions of etamsylate injection 0.5 g once daily and then ceftriaxone sodium for injection 0.5 g once daily successively. After 6 days of treatments, the boy′s gross hematuria disappeared. Routine urine analysis showed urine occult blood (+++), 3 red blood cells per high-power field in urine microscopy, and urine protein (+++). Eleven days later, the re-analysis showed urine occult blood (+), none red blood cell per high-power field in urine microscopy, and urine protein (++). One month later, the re-analysis showed urine occult blood ( -) and urine protein ( -).