Investigation and Optimization Strategy on the Compatibility of Drug Mixed Infusions in ICU of A Hospital
10.3870/j.issn.1004-0781.2025.04.024
- VernacularTitle:某院重症监护室药物混合输注的相容性调查分析及优化策略
- Author:
Liju FAN
1
;
Shuaining PENG
1
;
Xiaoyu ZHAO
1
;
Jing AN
1
;
Zhanjun DONG
1
Author Information
1. 河北省人民医院药学部,石家庄 050051;河北省临床药学重点实验室,石家庄 050051
- Publication Type:Journal Article
- Keywords:
Intensive care unit;
Intravenous medications;
Infusion mixing;
Compatibility
- From:
Herald of Medicine
2025;44(4):656-661
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the compatibility of commonly used intravenous drugs in the ICU of Hebei General Hospital and to propose optimization strategies.Methods Data from 35 intravenous drugs used in ICU from January 1 to December 31,2023 were analyzed using the Micromedex database and relevant literature.Results A compatibility chart for 35 drugs was created.Total 595 combinations,of which 279(46.9％)were compatible,22(3.7％)were incompatible,28(4.7％)were uncertain,and 266(44.7％)were unknown.Conclusion Drug co-administration is common in the ICU,but there is a lack of safety evidence and guidelines.There is an urgent to improve compatibility data and develop comprehensive resources to ensure safer intravenous drug administration.
