Urinary incontinence due to colchicine
10.3760/cma.j.cn114015-20191230-01101
- VernacularTitle:秋水仙碱致尿失禁
- Author:
Xiting TANG
1
;
Guilong XIE
Author Information
1. 四川省甘孜藏族自治州人民医院药剂科，康定 626000
- Publication Type:Journal Article
- Keywords:
Colchicine;
Gout suppressants;
Urinary incontinence
- From:
Adverse Drug Reactions Journal
2020;22(10):589-590
- CountryChina
- Language:Chinese
-
Abstract:
A 55-year-old male patient with hepatic complex alveolar echinococcosis, who had a history of gout for more than 4 years, developed swelling and high skin temperature of feet when he waited for the result of remote consultation and prepared for optional right hemihepatectomy in the hospital. Laboratory tests showed that uric acid was 530 μmol/L and rheumatic factor was negative. Acute gout attack was considered. He was treated with oral colchicine 0.5 mg thrice daily. About 10 hours after the first administration, the patient developed urinary incontinence. According to the consultation results, it was considered that the urinary incontinence might be related to colchicine. Colchicine was stopped immediately. The symptoms of urinary incontinence disappeared 24 hours after drug withdrawal. The symptoms of urinary incontinence recurred after the patient took the drug again by himself. Urinary incontinence did not recur after the colchicine withdrawal again.
