Effect evaluation of Kushen Huangqi decoction combined with Aidi injection in the treatment of primary liver cancer
- VernacularTitle:苦参黄芪汤联合艾迪注射液治疗原发性肝癌的效果评价
- Author:
Guanghua YU
1
;
Chunyan SONG
;
Xue SONG
Author Information
- Publication Type:Journal Article
- Keywords: Ai Di Zhu She Ye; drug therapy,combination; drug evaluation; quality of life; Kushen Huangqi Decoction; primary liver cancer; immune function
- From: Tianjin Medical Journal 2025;53(4):429-433
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the therapeutic effect of Kushen Huangqi decoction combined with Aidi injection on primary liver cancer and its impacts on immune function and quality of life.Methods A total of 110 patients with primary liver cancer were randomly divided into the combined group(n=55)and the control group(n=55).The control group was treated with Aidi injection(50 mL)on the basis of routine treatment,and the combined group was treated with Kushen Huangqi decoction on the basis of the control group.The healing effects,traditional Chinese medicine(TCM)symptom scores,quality of life[Karnofsky Performance Status(KPS)score,the MOS 36-item short-form health survey(SF-36)],liver function indicators[total bilirubin(TBIL),aspartate aminotransferase(AST),alanine aminotransferase(ALT)]and immune function indicators before and after treatment were compared between the two groups.Results After treatment,the KPS score,SF-36 score,CD4+and CD4+/CD8+were increased in the two groups,and those in the combined group were higher than the control group.The TCM symptom scores,AST,TBIL,ALT and CD8+were decreased in the two groups,and those in the combined group were lower than those in the control group(P＜0.05).Conclusion The combination of Kushen Huangqi decoction and Aidi injection is beneficial for enhancing immune function,reducing Chinese medicine syndrome scores and liver function damage,improving efficacy and quality of life in treating primary liver cancer.
