Trajectories of executive function development and its neural mechanisms in patients with attention deficit hyperactivity disorder
10.3760/cma.j.cn371468-20240924-00436
- VernacularTitle:注意缺陷多动障碍患者执行功能发育轨迹及神经机制
- Author:
Ruilin JIN
1
;
Jiaqi ZHOU
;
Teng ZHU
;
Jiayun YU
;
Wanying ZHENG
;
Hanlin LI
;
Mengjie ZHANG
;
Xiaolei CEN
;
Chuang YANG
Author Information
1. 温州医科大学精神医学学院，温州 325035
- Publication Type:Journal Article
- Keywords:
Attention deficit hyperactivity disorder;
Executive functions;
Development;
Neural mechanisms
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2025;34(3):277-282
- CountryChina
- Language:Chinese
-
Abstract:
Executive function(EF) is an advanced cognitive function of the central nervous system, and is closely related to an individual's capacity for daily living and adaptation. Patients with attention deficit hyperactivity disorder (ADHD) typically exhibit significant executive dysfunction. While most existing studies on the executive function of individuals with ADHD are cross-sectional, and little is known about the longitudinal maturation process of related brain structures and functional connectivity patterns. The findings indicate that ADHD patients exhibit differential developmental trajectories in brain structural and functional connectivity compared with typically developing group.Furthermore, there is a lifespan association between abnormal brain network development and ADHD symptoms. This article aims to elucidate the characteristics of executive function deficits in ADHD patients across different developmental stages, examining their relationship with the nervous system’s development from a development perspective.
