Relationship between intolerance of uncertainty and fear of disease progression in patients with intracranial aneurysms: chain mediating role of submission and illness perception
10.3760/cma.j.cn371468-20240806-00355
- VernacularTitle:屈服和疾病感知在颅内动脉瘤患者无法忍受不确定性和疾病进展恐惧间链式中介效应
- Author:
Jingyi ZHU
1
;
Xiaoyan WANG
;
Shuyin LIANG
;
Yunji WANG
;
Jiayan HUANG
;
Chen SHI
;
Hongzhen ZHOU
Author Information
1. 南方医科大学南方医院，广州 510515
- Publication Type:Journal Article
- Keywords:
Intracranial aneurysms;
Fear of disease progression;
Intolerance of uncertainty;
Medical coping style;
Illness perception;
Submission;
Chain mediating model
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2025;34(3):229-235
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the chain mediating effect of coping style and illness perception between intolerance of uncertainty and fear of disease progression in patients with intracranial aneurysm.Methods:A total of 270 patients with intracranial aneurysms admitted to the neurosurgery department of 2 hospitals in Guangzhou from October 2023 to June 2024 were selected by convenience sampling method. The general information questionnaire, intolerance of uncertainty scale-12, the brief disease perception questionnaire, medical coping mode questionnaire(MCMQ) and fear of progression questionnaire-short form were used to investigate the subjects. Statistical description and Spearman correlation analysis were performed using IBM SPSS 25.0 software, and AMOS 23.0 software was used to test and correct the structural equation models.Results:The total score of fear of disease progression in patients with intracranial aneurysms was 27.50(20.00, 34.00). The total score of intolerance of uncertainty was 23.50(19.75, 29.00). The sores of confrontation, avoidance and submission in MCMQ were 18.69±5.44, 12.00(10.00, 15.00) and 7.00(5.00, 9.00), respectively.The total score of illness perception was 37.23±11.60. Fear of disease progression was positively correlated with intolerance of uncertainty, submission and illness perception ( r=0.614, 0.696, 0.680, all P<0.01). The direct effect of intolerance of uncertainty on fear of disease progression was significant in patients with intracranial aneurysms ( β=0.431, P<0.001). Intolerance of uncertainty indirectly affected fear of disease progression through submission ( β=0.181, P<0.001) and illness perception ( β=0.092, P<0.001). Submission and illness perception played chain-mediating effect in the relationship between intolerance of uncertainty and fear of disease progression ( β=0.103, P<0.001). Conclusion:The intolerance of uncertainty in patients with intracranial aneurysms can positively predict the fear of disease progression. Submission and illness perception played a chain mediating role between intolerance of uncertainty and fear of disease progression in patients with intracranial aneurysms.
