A case of transcatheter edge-to-edge repair performed on a patient with severe atrial functional mitral and tricuspid regurgitation
10.3969/j.issn.1004-8812.2025.04.009
- VernacularTitle:经导管缘对缘修复治疗房性功能性二尖瓣、三尖瓣重度反流1例
- Author:
Yi-jiang ZHOU
1
;
Wei-cong XIA
;
Kai WANG
;
Jun LI
;
Ya-wei CUI
;
Kai-li WANG
;
Yun MOU
;
KUSHANI·REYIHAN
;
Xiao-gang GUO
Author Information
1. 浙江大学医学院附属第一医院心血管内科,浙江 杭州 310006
- Publication Type:Journal Article
- Keywords:
Transcatheter edge-to-edge repair;
Mitral regurgitation;
Tricuspid regurgitation
- From:
Chinese Journal of Interventional Cardiology
2025;33(4):236-240
- CountryChina
- Language:Chinese
-
Abstract:
Persistent atrial fibrillation and other factors can cause mitral and tricuspid annular dilation and leaflet regurgitation,leading to severe functional mitral and tricuspid regurgitation.Patients often experience significant heart failure symptoms and poor prognosis.For patients with severe mitral or tricuspid regurgitation who are at high risk or contraindicated for surgical procedures,transbronchial repair(TEER)is an important alternative therapy that can effectively reduce valve regurgitation and improve cardiac function;Although there is a lack of large-scale data on atrial functional reflux,existing experience still shows that TEER can significantly reduce reflux and improve patients'quality of life.However,double valve intervention therapy poses challenges,especially when combined with TEER repair,which is technically more complex,time-consuming,and carries higher risks.Foreign data shows that simultaneous or staged double valve intervention can safely improve cardiac function and increase survival rates,but the optimal intervention strategy still needs further research.Due to the fact that tricuspid TEER devices have not yet been launched in China,only staged treatment can be adopted at present.This case report shows a patient with severe atrial functional mitral and tricuspid regurgitation who underwent staged transcatheter edge to edge repair surgery successfully.During a 1-year follow-up,bilateral valve regurgitation continued to improve,indicating that staged repair of bilateral atrioventricular valve regurgitation through the catheter margin is a feasible and effective treatment option.