Advances in the mechanisms and ablation strategies of left posterior fascicular ventricular tachycardia
10.3969/j.issn.1004-8812.2025.04.006
- VernacularTitle:左后分支型室性心动过速的发病机制与消融策略进展
- Author:
Di DING
1
Author Information
1. 复旦大学附属中山医院青浦分院心血管内科 上海市青浦区中心医院,上海 201700
- Publication Type:Journal Article
- Keywords:
Left posterior fascicular ventricular tachycardia;
Reentry mechanism;
Radiofrequency ablation
- From:
Chinese Journal of Interventional Cardiology
2025;33(4):222-226
- CountryChina
- Language:Chinese
-
Abstract:
Left posterior fascicular ventricular tachycardia(LPFVT)is the most common subtype of verapamil-sensitive ventricular tachycardia,predominantly occurring in young patients without structural heart disease.Its underlying mechanism is primarily associated with reentrant activity within the Purkinje fiber network of the posterior septum of the left ventricle.With advancements in electrophysiological studies and radiofrequency catheter ablation(RFCA),treatment strategies for LPFVT have been progressively optimized,including targeted ablation based on Pl potentials,linear ablation in the mid-to-inferior septal region of the left ventricle,and novel mapping approaches targeting Fragmented Antegrade Purkinje Potentials(FAPs).Furthermore,recent studies have highlighted the potential roles of false tendons and ventricular myocardium in the reentrant circuit of LPFVT,enhancing our understanding of its complex pathophysiological mechanisms.The application of electroanatomical mapping technology has significantly improved the precision of intraoperative localization,providing safer and more effective therapeutic options for patients with non-inducible or non-sustained LPFVT.This review systematically discusses the pathophysiological mechanisms and ablation strategies of LPFVT,offering theoretical insights and practical guidance for its clinical management.
