A Behavior and Event-Related Potentials Study on the of the Effects of Long-Term Emotional Disturbance and Liver Failing to Govern Conveyance and Dispersion on Prospective Memory in Middle-Aged and Elderly People in the Community
- VernacularTitle:长期情志不畅肝失疏泄影响社区中老年人群前瞻记忆的行为学和事件相关电位研究
- Author:
Zhongpeng QIN
1
;
Xianghong ZHAN
;
Yong LIU
;
Junlin HOU
;
Ning LI
;
Ziwei ZHAO
;
Huanghong ZHAO
;
Lei HUO
;
Yan ZHANG
Author Information
- Publication Type:Journal Article
- Keywords: Long-term emotional disturbance; Liver failing to govern conveyance and dispersion; Dementia; Event-based prospective memory; Event-related potentials
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(3):739-751
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the neuroelectrophysiological mechanism of the decline of overall cognitive function and prospective memory,the syndrome manifestation of liver failing to govern conveyance and dispersion of the middle-aged and elderly people in the community with long-term emotional disturbance were evaluated.Methods Eysenck personality questionnaire(EPQ)and general condition questionnaire were used to screen the middle-aged and elderly people from 46 to 65 years old in the community who met the high and low neuroticism criteria,which were included in the long-term emotional disturbance group and the control group.According to the principle of matching sex,age(±2 years)and years of education(±2 years),60 subjects in each group were included.The scores of livers meridian syndrome,anxiety factor,depression factor and the total scores of three factors in the two groups were detected with the emotion rating scale for Ganzangxiang of traditional Chinese medicine.The overall cognitive function,the overall level of prospective memory and the dual-task paradigm of event-related memory were evaluated and event-related potential components were detected.Results Compared to the control group,the total scores of emotion rating scale for Ganzangxiang of traditional Chinese medicine and the scores of liver meridian syndrome factor,anxiety factor and depression factor all increased in the long-term emotional disturbance group significantly(P<0.05).The total scores of MoCA scale(after correction)and the level scores of visual space and executive function,attention and delayed recall decreased significantly(P<0.05),and the total scores of prospective memory questionnaire decreased significantly(P<0.05).The correct rates of ongoing tasks and prospective memory tasks in the event-based prospective memory dual task paradigm were decreased,and the reaction time was prolonged in the long-term emotional disorder group significantly(P<0.05).The amplitude of P200 of ongoing task and prospective memory task were increased in the long-term emotional disorder group(0.05
