Effect of individualized lifestyle intervention on sexual function in obese patients with polycystic ovary syndrome
10.3969/j.issn.1006-7795.2025.04.005
- VernacularTitle:个体化生活方式干预对多囊卵巢综合征肥胖患者性功能的影响
- Author:
Xuanxuan TIAN
1
;
Xiangyan RUAN
1
;
Yue ZHAO
1
;
Jing JIN
1
;
Shunyu LIU
1
;
Lingling JIANG
1
Author Information
1. 首都医科大学附属北京妇产医院/北京妇幼保健院内分泌科,北京 100026
- Publication Type:Journal Article
- Keywords:
polycystic ovary syndrome;
lifestyle intervention;
individuation;
obese;
sexual function;
sexual dysfunction
- From:
Journal of Capital Medical University
2025;46(4):614-619
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of individualized lifestyle intervention on sexual function in obese patients with polycystic ovarian syndrome(PCOS).Methods The study was conducted on obese patients with PCOS in the Department of Endocrinology,Beijing Obstetrics and Gynecology Hospital,Capital Medical University from October 2022 to December 2023.There were 160 cases in both the experimental group and the control group,progesterone was administered to both groups for 3 months to regulate menstruation.For women in the experimental group received individualized comprehensive lifestyle intervention combining diet,exercise,and behavior modifications,along with dedicated follow-up and weight management.The control group received routine clinical education for lifestyle intervention aimed at weight loss.Female Sexual Function Index(FSFI)and 12-item Short-Form Health Survey(SF-12)scale were applied to evaluate the sexual function and quality of life.The clinical data that may affect sexual function were collected and sex hormone levels were measured,including anthropometric indicators,estradiol,sex hormone-binding globulin,total testosterone,bioactive testosterone,and dehydroepiandrosterone sulfate in serum.Results After 3 months of intervention,the body mass index,waist circumference,body fat percentage,insulin resistance index,total testosterone,bioactive testosterone and dehydroepiandrosterone sulfate in experimental groups were significantly lower(P<0.05),and the sex hormone binding globulin level was significantly higher(P<0.001),compared with the control group.SF-12 mental health scores,FSFI total scores,sexual desire,orgasm and sexual satisfaction scores were significantly increased in experimental groups(P<0.05),however,there were no significant differences in SF-12 physical health scores,as well as the scores of sexual arousal,vaginal lubrication,and coital pain.Conclusions Individualized lifestyle intervention can better improve the sexual function and mental health of obese patients with PCOS.
