Analysis of the risk factors of the infarct growth rate in acute anterior circulation large vessel occlusion
10.3969/j.issn.1006-7795.2025.04.016
- VernacularTitle:急性前循环大血管闭塞性脑梗死进展速度的影响因素分析
- Author:
Xiaowen ZHANG
1
;
Tao TANG
;
Di LI
;
Shen LI
;
Chunjiang XI
Author Information
1. 首都医科大学附属北京世纪坛医院神经与精神科,北京 100038
- Publication Type:Journal Article
- Keywords:
large vessel occlusion;
cerebral infarction;
infarct growth rate;
risk factor;
hypertension;
atrial fibrillation;
internal carotid artery occlusion
- From:
Journal of Capital Medical University
2025;46(4):688-693
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of the infarct growth rate(IGR)in patients with acute anterior circulation large vessel occlusion.Methods This is a retrospective analysis of consecutive patients having acute anterior circulation large-vessel occlusion and being admitted to the Department of Neurointerventional Intervention,Central Hospital affiliated to Dalian University of Technology between September 2021 and July 2023.Patients were dichotomized into rapid and slow growth groups based on the median value of IGR,with 145 cases in each group.Univariate and multivariate Logistic regression models were used to analyze the risk factors of preoperative IGR.Results Multivariable Logistic regression analysis,after univariate screening,showed that hypertension(OR=2.27,95%CI:1.39-3.71),atrial fibrillation(OR=1.95,95%CI:1.22-3.12),and intracranial internal carotid artery occlusion(OR=1.98,95%CI:1.19-3.28)were risk factors of preoperative IGR(P<0.05).Hypertension,atrial fibrillation,and internal carotid artery occlusion all exhibited relatively low predictive value for IGR(P<0.05).The area under the curve for predicting IGR by combining these three factors was 0.642(95%CI:0.579-0.704),indicating a slight improvement in predictive performance,yet it remained relatively low.Conclusion Hypertension,atrial fibrillation,and proximal occlusion are risk factors of IGR in patients having acute anterior circulation large vessel occlusion.
