Research progress on the long-term effects of subthalamic nucleus deep brain stimulation on non-motor symptoms in Parkinson's disease
10.3969/j.issn.1006-7795.2025.04.023
- VernacularTitle:丘脑底核脑深部电刺激对帕金森患者非运动症状长期疗效研究进展
- Author:
Chenguan JIANG
1
;
Yan LIU
1
;
Zhou YANG
1
;
Bingxin LI
1
;
Jianguo ZHANG
1
;
Lin SHI
1
Author Information
1. 首都医科大学附属北京天坛医院神经外科学中心,北京 100070
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
subthalamic nucleus;
deep brain stimulation;
cognitive function;
affective disorders;
autonomic dys-function
- From:
Journal of Capital Medical University
2025;46(4):733-741
- CountryChina
- Language:Chinese
-
Abstract:
Deep brain stimulation(DBS)has witnessed rapid advancement as a neurosurgical intervention over the past four decades,addressing movement disorders and a spectrum of neuropsychiatric conditions.Notably,subthalamic nucleus deep brain stimulation(STN-DBS)is widely implemented in the management of Parkinson's disease(PD)patients experiencing refractory motor fluctuations and complications,and has shown promise in ameliorating non-motor symptoms(NMS).However,the long-term efficacy of STN-DBS on NMS remains a subject of scholarly discourse.This review endeavors to synthesize current knowledge regarding the long-term impacts,underlying mechanisms,and future research directions of STN-DBS in the context of NMS in Parkinson's disease.
