Comparative analysis of fine needle aspiration cytology and histopathology in axil-lary lymph nodes
10.13315/j.cnki.cjcep.2025.04.009
- VernacularTitle:乳腺腋窝淋巴结细针穿刺细胞学与组织病理学对照分析
- Author:
Boya ZHAI
1
;
Zhendong HUANG
1
;
Jinxing ZHOU
1
;
Yan WU
1
;
Lei XI
1
;
Cong WANG
1
;
Zhihong ZHANG
1
;
Rong RONG
1
Author Information
1. 南京医科大学第一附属医院/江苏省人民医院病理科,南京 210029
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
fine needle aspiration cytology;
cytology;
neoadjuvant therapy
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(4):469-473
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the role of ultrasound-guided fine needle aspiration cytology(US-FNAC)in the diagnosis of breast cancer.Methods Fine needle aspiration cytology(FNAC)samples of 203 patients with breast cancer were selected and prepared by liquid-based cytology.The results of histopathology after neoadjuvant therapy were used as the gold standard to compare with the diagnostic results of FNAC samples,and then evaluated the diagnos-tic coincidence rate of FNAC samples.Results Of 203 axillary lymph node FNAC samples,111 cases were diagnosed as positive,38 cases were diagnosed as suspicious for positivity,and 54 cases were diagnosed as negative.The diag-nostic accuracy of FNAC was 85.2％,the sensitivity of FNAC was 98.0％,and the specificity of FNAC was 90.0％.Conclusion FNAC has high sensitivity and accuracy in the diagnosis of axillary lymph node metastasis.Sentinel lymph node biopsy is recommended for patients with negative FNAC but clinically and radiographically suspected lymph node metastasis.
