Research progress in animal models of influenza virus/Streptococcus pneumoniae co-infection
10.3969/j.issn.1671-7856.2025.03.015
- VernacularTitle:IV/SPN共感染动物模型的研究进展
- Author:
Jianshu YANG
1
;
Xuefeng WANG
;
Xiuying ZHANG
;
Jingwen MU
;
Wentao XU
Author Information
1. 辽宁中医药大学,沈阳 110847
- Publication Type:Journal Article
- Keywords:
influenza virus;
Streptococcus pneumoniae;
co-infection;
animal model
- From:
Chinese Journal of Comparative Medicine
2025;35(3):170-178
- CountryChina
- Language:Chinese
-
Abstract:
Bacterial reinfection in the lungs of patients with influenza virus(IV)is a key factor leading to serious illness and death.The adverse consequences caused by co-infection with IV and Streptococcus pneumoniae(SPN)impose a serious burden on patients.However,the specific pathogenesis is complex,how to make better use of the mouse animal model of IV/SPN co-infection for subsequent basic research is of great significance.This article reviews the selection of animals,the selection of pathogen types,the selection of different modeling times,the identification of the co-infection model,and its applications in the IV/SPN co-infection model,so as to provide a reference for the selection of animal models of IV/SPN co-infection in the future.
