Application of nomogram in the research on association between ocular be-havior and myopia in preschool children
10.13389/j.cnki.rao.2025.0094
- VernacularTitle:列线图在学龄前儿童用眼行为与近视相关性研究中的应用
- Author:
Xiaolian XIE
1
;
Liping LI
;
Bing WANG
;
Juan MA
;
Qi CHEN
;
Haiping ZHAO
;
Juan CAO
Author Information
1. 750004 宁夏回族自治区银川市,宁夏医科大学公共卫生学院;750001 宁夏回族自治区银川市,中国人民武装警察部队宁夏回族自治区总队医院消毒供应科
- Publication Type:Journal Article
- Keywords:
preschool children;
myopia;
nomogram
- From:
Recent Advances in Ophthalmology
2025;45(7):539-545,553
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the association between eye-related behaviors and myopia among preschool chil-dren in Ningxia Hui Autonomous Region,and to develop a predictive nomogram model.Methods Using stratified cluster random sampling,36 062 preschool children from 400 randomly selected kindergartens in Ningxia Hui Autonomous Region were enrolled between October and December 2023.Primary caregivers of participants completed structured question-naires.Data were randomly split into a training set(n=25 243,70％)and a validation set(n=10 819,30％)in a ratio of 7∶3.The training set was used for model construction,and the validation set for external validation.Calibration plots and the Hosmer-Lemeshow(H-L)goodness-of-fit test assessed agreement between predicted and observed risks.Decision curve analysis(DCA)and clinical impact curve analysis(CICA)evaluated clinical utility.Results The myopia preva-lence among preschool children in Ningxia Hui Autonomous Region was 3.8％.A nomogram model based on binary Logistic regression showed area under the curve(AUC)values of 0.88(95％CI:0.87-0.89)for the training set and 0.89(95％CI:0.87-0.90)for the validation set,indicating strong discriminative ability.Calibration curves and H-L tests revealed good model fit(training set:x2=4.92,P=0.766;validation set:x2=5.52,P=0.961),with all P＞0.05.DCA and CICA confirmed clinical utility.The nomogram identified parental myopia,academic pressure,frequency of eye fatigue,daily screen time,and regular vision checks as the top five predictors of myopia.Conclusion The nomogram demonstrates promising potential for predicting myopia risk in preschool children in Ningxia Hui Autonomous Region,serving as a robust tool for clinical and educational myopia risk assessment.
