Organoids and Organ-on-Chips:Cutting-Edge Strategies for the Modernization of Chinese Medicine
10.14148/j.issn.1672-0482.2025.0847
- VernacularTitle:类器官和器官芯片:中医药现代化的前沿策略
- Author:
Xin HAN
1
;
Peiliang SHEN
;
Yuemei MA
;
Yuanyuan JIA
Author Information
1. 南京中医药大学 中药制药过程控制与智能制造技术全国重点实验室,江苏 南京 210023;南京中医药大学医学院,江苏 南京 210023
- Publication Type:Journal Article
- Keywords:
modernization of Chinese medicine;
microfluidic technology;
organoids and organoid-on-chips;
precision medicine;
holistic philosophy of Chinese medicine
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(7):847-855
- CountryChina
- Language:Chinese
-
Abstract:
Although significant progress has been made in the modernization of Chinese medicine,the current challenges,inclu-ding inconsistent diagnostic and treatment standards,complex molecular mechanisms,and insufficient safety evidence,have signifi-cantly restricted its modernization process.Microfluidic technology provides a new solution for Chinese medicine research with its ability to precisely control fluids and construct bionic microenvironments.Organoid and organ-on-a-chip technologies use microfluidic tech-nology as carriers to provide technical support for the visualization of Chinese medicine theory,discovery of pharmacological sub-stances,analysis of action mechanisms,and toxicity evaluation through multi-organ interconnection models.These technological break-throughs provide an innovative platform for analyzing Chinese medicine theory,driving Chinese medicine research from empirical analy-sis to systematic and dynamic simulations,providing crucial technical support for Chinese medicine internationalization and precision medicine transformation.
