Research progress on magnesium metabolism disorders in patients with chronic kidney disease
10.3760/cma.j.cn341190-20250406-00443
- VernacularTitle:慢性肾脏病患者镁代谢紊乱研究进展
- Author:
You WU
1
;
Jiamei DI
Author Information
1. 蚌埠医科大学研究生院，蚌埠 233030
- Publication Type:Journal Article
- Keywords:
Kidney failure, chronic;
Chronic disease;
Kidney diseases;
Magnesium;
Electrolytes;
Metabolism;
Review
- From:
Chinese Journal of Primary Medicine and Pharmacy
2025;32(8):1276-1280
- CountryChina
- Language:Chinese
-
Abstract:
Magnesium metabolism disorders are very common in patients with chronic kidney disease, and precise management of blood magnesium levels is crucial for improving patient prognosis. Current studies indicate that low serum magnesium levels may exacerbate vascular calcification and inflammatory responses in these patients, interfere with glucose metabolism, and increase the risks of cardiovascular death and all-cause mortality. It is also closely associated with the development of hypertension, depression, and cognitive dysfunction. Conversely, a certain degree of elevated serum magnesium levels may help reduce blood pressure, improve vascular calcification and inflammatory status, and decrease the risks of all-cause mortality and fracture incidence. However, whether high serum magnesium levels can reduce the risk of cardiovascular death in patients with chronic kidney disease remains a controversial issue. This review aims to discuss the research progress on magnesium metabolism disorders in patients with chronic kidney disease from multiple perspectives.
