Exploring the Pathological Mechanism of Depression Based on the Similarity between the Brain Xuanfu and the Glymphatic System
10.14148/j.issn.1672-0482.2025.0889
- VernacularTitle:基于脑玄府与胶质淋巴系统的相似性探讨抑郁症的病理机制
- Author:
Hong TANG
1
;
Huijing LI
;
Dan WANG
;
Juan LI
;
Xiaobo LIU
;
Xingyi MA
;
Yuxi LI
;
Rongjiang JIN
;
Huan LIU
Author Information
1. 成都中医药大学针灸推拿学院,四川 成都 610075
- Publication Type:Journal Article
- Keywords:
depression;
glymphatic system;
brain Xuanfu;
pathological mechanism
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(7):889-895
- CountryChina
- Language:Chinese
-
Abstract:
It is proposed that the brain Xuanfu and the glymphatic system(GS)have commonality in physiological structure and similarity in functions such as transporting brain substances,transmitting brain information and clearing metabolites.It is believed that GS may be the substantial manifestation of the brain Xuanfu,and GS dysfunction is the key pathological link of depression.Xuanfu stagnation and Shenji dysfunction are the core pathogenesis of depression.Taking"Brain Xuanfu-GS"as the starting point,the patho-logical mechanism of depression is deeply explored,providing a theoretical basis for the clinical diagnosis and treatment of depression in traditional Chinese medicine.
