Analysis of influencing factors of major adverse cardio-cerebrovascular events after drug-eluting stenting in patients with coronary artery disease
10.3969/j.issn.1008-0074.2025.02.01
- VernacularTitle:冠状动脉疾病患者药物洗脱支架术后主要不良心脑血管事件发生的影响因素分析
- Author:
Zhao-yun MENG
1
;
Yan-qun ZHANG
;
Xiu-ling WANG
Author Information
1. 济南市人民医院全科医学科,山东济南 271100
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Drug-eluting stents;
Root cause analysis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2025;34(2):135-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influencing factors of major adverse cardio-cerebrovascular events(MACCE)after drug-eluting stenting in patients with coronary artery disease(CAD).Methods:Retrospective study data from First Affiliated Hospital of Zhengzhou University were extracted from the Dryad database.Patients were di-vided into MACCE group(n=160)and control group(n=880)according to whether MACCE occurred during fol-low-up.Clinical data including age,gender,fibrinogen(Fg)level etc.were compared between two groups,and the variables with significant differences between two groups were substituted into Logistic regression model to screen the influencing factors of MACCE after drug eluting stenting in CAD patients.Results:Compared with pa-tients in control group,those in MACCE group had significant higher Fg level[(3.6±1.1)g/L vs.(3.4±1.0)g/L],proportions of triple-vessel coronary disease(25.6％ vs.18.3％)and right coronary artery lesion(53.1％ vs.41.7％)(P＜0.05 or＜0.01).Multivariate Logistic regression analysis indicated that Fg level(OR=1.18,95％CI 1.01～1.37,P=0.039)was the independent risk factor of MACCE after drug eluting stenting in CAD patients.The risk of MACCE after drug eluting stenting in CAD patients significantly increased when the Fg level was＞3.27 g/L.Conclusion:High Fg level is the independent risk factor of MACCE after drug eluting stenting in CAD patients.
