Clinical characteristics and correlation analysis between serum vitamin D and bone mineral density in elderly patients with hip fractures
10.3760/cma.j.cn115807-20240523-00174
- VernacularTitle:老年髋部骨折患者临床特征和血清维生素D与骨矿物质密度相关性分析
- Author:
Lianyu ZHONG
1
;
Jun WU
;
Zeliang ZHANG
Author Information
1. 山西省汾阳医院急诊科，汾阳 032200
- Publication Type:Journal Article
- Keywords:
Emergency;
Elderly;
Hip fracture;
Clinical characteristics;
Vitamin D;
25-hydroxyvitamin D;
Bone density
- From:
Chinese Journal of Endocrine Surgery
2025;19(5):732-735
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical features of elderly patients with hip fracture and the expression of serum vitamin D (VitD), 25- hydroxy vitamin D (25-OH-D) and bone mineral density,, BMD) .Methods:Collect clinical data from 90 elderly patients with hip fractures admitted to the Emergency Department of Fenyang Hospital in Shanxi Province from Oct. 2020 to Dec. 2023 for analysis. Based on whether the patients have VitD deficiency, they were divided into group A (severe deficiency of 25-OH-D, insufficient) and group B (sufficient 25-OH-D). Clinical characteristics of patients and the levels of VitD, 25-OH-D, and BMD, and the correlation between the above indicators were analyzed.Results:The age of patients in groups A and B, whether there is osteoporosis, and 25-OH-D levels are suspicious influencing factors that cause VitD deficiency ( t=9.38, 5.06, 10.25 , P<0.05). There were statistical differences in lumbar vertebra, femoral neck, total hip BMD, lumbar vertebra SUVmen, total hip, lumbar SUVmax and indicators between group A and group B ( t=3.94, 9.21, 2.53, 3.95, 2.61 , P<0.05). Logistic regression analysis results showed that osteoporosis Exp[ (61.857 (3.029-1 263.408) , P<0.05], 25-OH-D[ (0.039 (0.005-0.312) , P<0.05], total hip BMD[ (480.040 (4.384-5 257.048) , P<0.05] were the main independent influencing factors causing VitD deficiency. Conclusions:There is a close relationship between 25-OH-D level, BMD expression and VitD deficiency in elderly patients with hip fractures. Among them, osteoporosis, 25-OH-D level, and total hip BMD are the main independent influencing factors that cause VitD deficiency.
