A qualitative study on the oral anti-cancer drug adherence of patients with hematological malignancies based on the BCW theory
10.3760/cma.j.cn211501-20241025-02930
- VernacularTitle:基于行为改变轮理论对血液肿瘤患者口服抗肿瘤药物依从性的质性研究
- Author:
Ziyi ZHANG
1
;
Haitao RUAN
1
Author Information
1. 华中科技大学同济医学院附属同济医院护理部，武汉 430000
- Publication Type:Journal Article
- Keywords:
Hematologic neoplasms;
Qualitative research;
Behaviour change wheel;
Oral antineoplastic drugs;
Compliance
- From:
Chinese Journal of Practical Nursing
2025;41(30):2353-2359
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the compliance status of oral antineoplastic drugs in patients with hematologic tumors based on behaviour change wheel(BCW) theoretical model, so as to provide reference for the construction of oral antineoplastic drug management model and intervention strategy for hematological tumors.Methods:From April to July 2024, a semi-structured interview was conducted with 20 patients with hematological malignancies who took oral antineoplastic drugs in the Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology by purposive sampling. Based on the ability, opportunity, motivation-behavior model in the BCW theory, an interview outline was designed. Then, by applying this theory model in combination with Colaizzi's 7-step analysis method, the interview data were analyzed, summarized, and themes were extracted.Results:A total of 20 patients complete the interview, there were 13 males and 7 females, aged from 21 to 91 years old, with an average age of 53 years old. Three themes and 10 sub-themes were extracted: behavioral source-ability (insufficient coping skills for continuous medication, lack of individualized drug side effect perception and coping ability, weak ability and cognition of safe medication), behavioral source-opportunity (social support factors, lack of continuous and effective doctor-patient communication platform, and persistent economic toxicity of drugs), and behavioral source-motivation (strong doctor-patient dependence, drug side effects, insufficient expected efficacy, treatment complexity, and psychological burden).Conclusions:The factors affecting the medication compliance of patients treated with oral antineoplastic drugs are complex and diverse, and medical staff need to carry out a comprehensive assessment of patients before treatment, formulate personalized education methods, and implement and improve diversified and multi-dimensional support models and auxiliary systems to improve patients' compliance, ensure patients' drug safety, maximize treatment effect, and improve disease prognosis.
