Value and mechanism of action of long non-coding RNA HOTAIR in early diagnosis of breast cancer
10.3969/j.issn.1005-6483.20240528
- VernacularTitle:长链非编码RNA HOTAIR在乳腺癌早期诊断中的价值和作用机制
- Author:
Di HU
1
;
Haoyuan SHEN
Author Information
1. 432100 武汉科技大学附属孝感医院(孝感市中心医院)甲状腺乳腺外科;武汉科技大学医学院
- Publication Type:Journal Article
- Keywords:
breast cancer;
HOTAIR;
early diagnosis
- From:
Journal of Clinical Surgery
2025;33(3):329-331
- CountryChina
- Language:Chinese
-
Abstract:
At present,breast cancer is still the first place in the global incidence and mortality of female cancer.Searching for reliable biological markers plays an extremely important role in clarifying the early diagnosis of breast cancer and improving the long-term survival rate and prognosis of breast cancer patients.In recent years,long non-coding RNA HOTAIR(LncRNA HOTAIR)is still the focus of research by many scholars,and HOTAIR is closely related to the occurrence and development of a variety of malignant tumors.The expression of HOTAIR is particularly obvious in breast cancer patients.More and more studies have shown that HOTAIR is highly expressed in both peripheral blood and breast cancer tissues of breast cancer patients,and is closely related to the proliferation,metastasis and drug resistance of breast cancer.HOTAIR may become an important biomarker for the early diagnosis of breast cancer and a target for breast cancer treatment.
