Effects of different concentrations of ropivacaine in ultrasound-guided paravertebral nerve block combined with general anesthesia on postoperative recovery quality of patients undergoing radical resection of esophageal cancer
10.3760/cma.j.cn115807-20250416-00107
- VernacularTitle:超声引导下椎旁神经阻滞复合全身麻醉中不同罗哌卡因浓度对食管癌根治术患者术后苏醒质量的影响
- Author:
Lin LIN
1
;
Li KONG
1
;
Songmei MA
1
;
Xiaohui DONG
1
Author Information
1. 商丘市第一人民医院麻醉科，商丘 476100
- Publication Type:Journal Article
- Keywords:
Ultrasound;
Paravertebral nerve block;
General anesthesia;
Ropivacaine concentration;
Radical resection of esophageal carcinoma;
Quality of awakening
- From:
Chinese Journal of Endocrine Surgery
2025;19(3):418-423
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of different concentrations of ropivacaine on the quality of postoperative recovery in patients undergoing radical resection of esophageal cancer under ultrasound guided thoracic paravertebral nerve block (TPVB) combined with general anesthesia.Methods:The clinical data of 97 patients with radical resection of esophageal cancer treated from Jun. 2022 to Jan. 2025 in Shangqiu First People’s Hospital were retrospectively analyzed.All patients underwent ultrasound-guided TPVB combined with general anesthesia,and were divided into group A (0.25%) and group B (0.5%) according to the intraoperative ropivacaine concentration.The analgesic effect at extubation,2 hours and 12 hours after surgery was evaluated by VAS score.The cerebral oxygen metabolism indicators at tracheal intubation,15 minutes after the start of surgery and extubation were evaluated by CERO 2 and Da-jvO 2.The indicators related to recovery and the occurrence of adverse reactions were statistically analyzed.The quality of recovery was evaluated by QoR-40 score. Results:VAS scores were compared between the two groups; At 2 h and 12 h after surgery, VAS scores in both groups were higher than those at extubation, and lower at 12 h than at 2 h after surgery ( P<0.05). There were significant differences in CERO 2 and Da-jvO 2 between groups, time and interaction between groups A and B ( P<0.05). CERO 2 and Da-jvO 2 in both groups were higher than those in tracheal intubation 15min after operation. At extubation, CERO 2 and Da-jvO 2 in both groups were lower than those at tracheal intubation and 15 minutes after operation ( P<0.05). During endotracheal intubation, there was no significant difference in CERO 2 or Da-jvO 2 between the two groups ( P>0.05). CERO 2 and Da-jvO 2 in group A were lower than those in group B at 15min after operation and extubation ( P<0.05). The recovery time in group A was shorter than that in group B, and the QoR-40 score was higher than that in group B ( P<0.05). The total incidence of adverse reactions had no statistical difference between the two groups ( P>0.05) . Conclusion:The application of 0.25% ropivacaine in ultrasound-guided TPVB combined with general anesthesia can shorten the postoperative recovery time and improve the recovery quality of patients undergoing radical resection of esophageal cancer.
