Correlation analysis of oral cleanliness and secondary pulmonary infection in patients with severe COPD with mechanical ventilation
10.3760/cma.j.cn211501-20240709-01798
- VernacularTitle:重症COPD机械通气患者口腔清洁度与其继发性肺部感染的相关性分析
- Author:
Hongwang HAO
1
;
Lu XIANG
;
Yuecheng GU
;
Zhinan WANG
;
Guangren HU
;
Fulian ZHANG
Author Information
1. 杭州市第一人民医院城北院区（杭州市老年病医院）重症病房，杭州 310000
- Publication Type:Journal Article
- Keywords:
Pulmonary disease, chronic obstructive;
Oral cleanliness;
Lung infection;
Mechanical ventilation;
Correlation analysis
- From:
Chinese Journal of Practical Nursing
2025;41(20):1566-1572
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between oral cleanliness and secondary Pulmonary infection in patients with severe chronic obstructive pulmonary disease (COPD) in mechanical ventilation, and to investigate the predictive effect of oral cleanliness on the risk of secondary pulmonary infection.Methods:Using the cross-sectional survey method, the purposeful sampling method was adopted to select 216 patients with severe COPD who were hospitalized in Hangzhou First People′s Hospital from June 2020 to December 2023 and received mechanical ventilation. The oral cleanliness index and general clinical data of patients at admission were collected using the hospital electronic medical record system. The independent influencing factors of secondary lung infection were analyzed by univariate analysis and multivariate Logisitic regression. The predictive value of oral cleanliness index on secondary lung infection was analyzed by patient operating characteristic (ROC) curve.Results:216 patients with severe COPD who underwent mechanical ventilation were included.Patients aged 37-84 (66.81 ± 8.98) years were included, including 125 males and 91 females.Among them, 89 cases developed secondary pulmonary infection, with an infection rate of 41.20%.Univariate analysis and multivariate Logistic regression analysis showed that, Beck Oral Rating Scale (BOAS) score ( OR = 1.371), visual simulation score of oral odor ( OR = 1.405), gum index ( OR = 3.508), plaque index ( OR = 14.357), smoking history ( OR = 6.772), duration of disease ( OR = 1.391), COPD assessment test score ( OR = 1.269) and mechanical ventilation time ( OR = 1.302) were independent factors for secondary pulmonary infection (all P<0.05). ROC curve analysis showed that oral cleanliness index combined with infection prediction was effective (the area under the ROC curve was 0.833) . Conclusions:Oral cleanliness was closely related to secondary pulmonary infection in patients with severe COPD with mechanical ventilation. BOAS score, visual simulation score of oral odor, gingival index and plaque index could predict secondary pulmonary infection independently, and combined test could predict secondary pulmonary infection.
