Application of combined stent and catheter thrombectomy technique in severe cerebral venous sinus thrombosis
10.3760/cma.j.cn341190-20240516-00578
- VernacularTitle:支架联合导管复合取栓技术在重症静脉窦血栓中的应用研究
- Author:
Lin XIANG
1
;
Genlong ZHONG
1
;
Yanan TANG
1
;
Weikang CHEN
1
Author Information
1. 丽水市人民医院神经内科，丽水 323000
- Publication Type:Journal Article
- Keywords:
Sinus thrombosis,intracranial;
Balloon embolectomy;
Stents;
Catheters;
Anticoagulants;
Heparin;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2025;32(8):1132-1136
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of combined stent and catheter thrombectomy technique on severe cerebral venous sinus thrombosis.Methods:A single-center, prospective, randomized controlled study was conducted involving 78 patients with severe cerebral venous sinus thrombosis who were treated at Lishui People's Hospital from January 2019 to December 2023. Using the random number table method, these patients were divided into two groups: an experimental group ( n = 39) and a control group ( n = 39). The control group received heparin anticoagulation treatment, while the experimental group underwent stent placement combined with catheter thrombectomy. The patency rate of occluded venous sinuses, Glasgow Coma Scale scores, Glasgow Outcome Scale scores, overall prognosis, and the incidence of adverse events were compared between the two groups. Results:After treatment and at 90 days post-treatment, the patency rate of occluded venous sinuses in the experimental group was 89.7% (35/39) and 79.5% (31/39), respectively. These were significantly higher than those in the control group [71.8% (28/39), 56.4% (22/39), χ2 = 4.04, 4.77, both P < 0.05]. Both the Glasgow Coma Scale scores and Glasgow Outcome Scale scores significantly increased in both groups after treatment, with the experimental group showing higher scores than the control group (all P < 0.05). At 30 and 90 days after treatment, the proportion of patients with a modified Rankin Scale score of ≤ 2 in the experimental group was 87.2% (34/39) and 79.5% (31/39), respectively. These were significantly higher than those in the control group [66.7% (26/39), 53.8% (21/39), χ2 = 4.62, 5.77, both P < 0.05]. There was no significant difference in the total incidence of adverse events between the two groups ( P > 0.05). Conclusions:The stent combined with catheter thrombectomy technique exhibits a considerable application value for patients with severe cerebral venous sinus thrombosis. This approach can enhance the vascular recanalization rate, promote disease recovery, improve patient prognosis, and is considered safe.
