Logistic regression analysis of risk factors for cough-variant asthma
10.3760/cma.j.cn341190-20241101-01428
- VernacularTitle:基于logistic回归分析探究咳嗽变异性哮喘发生的危险因素
- Author:
Zhenping HAN
1
;
Ying CHEN
1
Author Information
1. 濮阳油田总医院内科，濮阳 457000
- Publication Type:Journal Article
- Keywords:
Asthma;
Cough;
Logistic models;
Respiratory tract infections;
Rhinitis, allergic;
Dermatitis, contact;
Interleukin-1;
Risk factors
- From:
Chinese Journal of Primary Medicine and Pharmacy
2025;32(7):1001-1005
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors for cough-variant asthma (CVA) based on logistic regression analysis.Methods:A retrospective analysis was conducted on 150 patients with CVA (observation group) and 135 patients without CVA (control group) who received treatment at the Department of Respiratory Medicine, Puyang Oilfield General Hospital from January 2021 to January 2024. The risk factors for CVA were screened.Results:Compared with the control group, the observation group showed significantly higher proportions of patients with respiratory tract infections [24.00% (36/150) vs. 10.37% (14/135), χ2= 9.12, P = 0.003], a history of allergic rhinitis [23.33% (35/150) vs. 8.89% (12/135), χ2 = 10.77, P = 0.001], a history of allergic dermatitis [18.67% (28/150) vs. 5.93% (8/135), χ2 = 10.45, P = 0.001], and a first-degree family history of allergies [32.67% (49/150) vs. 15.56% (21/135), χ2 = 11.23, P < 0.001], Additionally, a higher percentage of patients in the observation group had elevated levels of interleukin-1 [32.00% (48/150) vs. 8.89% (12/135), χ2 = 22.83, P < 0.001]. There were no statistically significant differences in gender, body mass index, oxygen environment, or pet ownership between the two groups (all P > 0.05). Logistic regression analysis showed that respiratory tract infection [ OR = 1.958, 95% CI: (1.182, 2.658)], allergic rhinitis history [ OR = 3.022, 95% CI: (3.310, 4.316)], allergic dermatitis history ( OR = 3.313, 95% CI: (3.893, 4.725)], first-degree family history [ OR = 5.023, 95% CI: (7.312, 8.138)], and elevated interleukin-1 levels ( OR = 3.050, 95% CI: (2.734, 3.365)] were risk factors for the occurrence of CVA. Conclusions:Respiratory tract infection, allergic rhinitis history, allergic dermatitis history, first-degree family history, and elevated interleukin-1 levels are risk factors for the occurrence of CVA.
