Progress in autologous fat grafting for scar treatment
10.3969/j.issn.1006-5725.2025.09.022
- VernacularTitle:自体脂肪移植治疗瘢痕的研究进展
- Author:
Xifeng AN
1
;
Xuan LIAO
1
;
Hongwei LIU
1
Author Information
1. 暨南大学第一附属医院整形外科,暨南大学整形外科新技术研究所,再生医学教育部重点实验室(广东 广州 510630)
- Publication Type:Journal Article
- Keywords:
scar;
autologous fat grafting;
adipose-derived stem cells;
regenerative medicine
- From:
The Journal of Practical Medicine
2025;41(9):1425-1432
- CountryChina
- Language:Chinese
-
Abstract:
Scarring is a key issue in plastic surgery research and there are limitations in the clinical outcomes of existing scar treatments.Autologous fat grafting is a new method that has been clinically proven to be effective in the treatment of pathological scarring.Autologous fat grafts contain adipose-derived mesenchymal stem cells and a variety of active factors that can effectively improve the appearance,texture and local symptoms of keloid scars through the mechanisms of immunomodulation of the inflammatory response,pro-angiogenesis,pro-cellular differentiation,extracellular matrix remodelling and resistance to oxidative stress damage,etc.It has the advantages of fewer complications and better therapeutic effect,and is a brand new field of keloid scar,which provides a new therapeutic direction for the keloid scar.The new field of scar treatment provides a new direction for scar treatment.The application and mechanism of autologous fat grafting in keloid scar is now reviewed,with the aim of providing a theoretical basis for the treatment of keloid scar and summarising the progress of its application in keloid scar treatment.
