Cortical activation characteristics in patients with post-stroke foot drop during task-oriented ankle reha-bilitation robot raining
10.3969/j.issn.1001-1242.2025.04.006
- VernacularTitle:任务导向性踝关节康复机器人训练对脑卒中足下垂患者皮质激活特征的研究
- Author:
Guangyi WANG
1
;
Qingfang ZHANG
;
Jie YAN
Author Information
1. 深圳市第二人民医院,广东省 深圳市,518035
- Publication Type:Journal Article
- Keywords:
stroke;
foot drop;
ankle rehabilitation robot;
task-oriented training;
functional near-infrared spec-troscopy;
cortical activation
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(4):516-521
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the cortical activation characteristics of patients with post-stroke foot drop during task-oriented ankle rehabilitation robot training using functional near-infrared spectroscopy(fNIRS).Method:Twenty patients with post-stroke foot drop were recruited.A 51-channel fNIRS system were used to measure changes in oxygenated hemoglobin(HbO2)in the cortical regions during task-oriented ankle rehabilita-tion robot training.The regions of interest(ROIs)included the bilateral dorsolateral prefrontal cortex(DLP-FC),primary motor cortex(M1),primary somatosensory cortex(S1),premotor area and supplementary mo-tor area(pSMA),and inferior frontal gyrus(IFG).Data processing and statistical analysis were conducted us-ing MATLAB(R2021b)and SPSS 25.0 software.Result:Significant cortical activation was observed in channels 19,26,28,29,35,36,39,42,and 48(P＜0.05)during task-oriented ankle rehabilitation robot training in patients with post-stroke foot drop.Based on the channel-to-brain region registration,significant activation was noted in the bilateral pSMA,bilateral DLPFC,unaffected side S1,and unaffected side IFG's area.Conclusion:Task-oriented ankle rehabilitation robot training can lead to increased cortical activation in pa-tients with post-stroke foot drop,which may represent a potential neural mechanism underlying its therapeutic effects.
