Research progress on mechanism of paeonol in the treatment of intestinal diseases
10.3969/j.issn.1006-5725.2025.10.024
- VernacularTitle:丹皮酚治疗肠道疾病作用机制研究进展
- Author:
Wei WANG
1
;
Shihua LU
1
;
Honghao ZHANG
1
;
Hualiang DENG
1
Author Information
1. 山东中医药大学附属医院消化内二科(山东 济南 250012)
- Publication Type:Journal Article
- Keywords:
paeonol;
intestinal diseases;
mechanism in the treatment;
research progress
- From:
The Journal of Practical Medicine
2025;41(10):1597-1602
- CountryChina
- Language:Chinese
-
Abstract:
As the lifestyle of modern people changes,genetic factors continue to become more prominent,and the impact of environmental and water pollution,the incidence of intestinal diseases(colorectal cancer,inflammatory bowel disease,irritable bowel syndrome,chronic constipation,etc.)is increasing.It not only seriously endangers the health of the population,but also consumes a large amount of medical resources.Paeonol,as a class of small molecule phenolic compounds,has a wide range of biological activities,such as anti-inflammatory,anti-viral,anti-tumor,anti-allergic,immune regulation,cardiovascular and cerebrovascular protection,etc.The mechanism and experimental research on the effect of paeonol in preventing and treating intestinal diseases based on the"Brain-Gut-Bacteria axis"are also in-depth.This article aims to systematically review and sort out the latest progress in this field,with a view to providing certain ideas and methods for the precise treatment of intestinal diseases and the development of new drugs.
