One case report of IVF-ET for a patient with malignant peritoneal mesothelioma after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy
10.3760/cma.j.cn101441-20250605-00255
- VernacularTitle:恶性腹膜间皮瘤细胞减灭术联合腹腔热灌注化疗后行IVF-ET助孕治疗的1例病案报道
- Author:
Ting LUO
1
;
Yunyan WANG
;
Caixia YUAN
;
Haixia SONG
Author Information
1. 山西医科大学第五临床医学院，太原 030012
- Publication Type:Journal Article
- Keywords:
In vitro fertilization;
Infertility;
Embryo transfer;
Peritoneal mesothelioma
- From:
Chinese Journal of Reproduction and Contraception
2025;45(11):1171-1174
- CountryChina
- Language:Chinese
-
Abstract:
Malignant peritoneal mesothelioma (MPM), as a highly aggressive primary malignant tumor of the peritoneum, often leads to structural damage and functional impairment of female reproductive organs during its treatment course. This study presents a clinical case of an MPM patient who underwent cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC), subsequently achieving successful live birth through in vitro fertilization and embryo transfer. A comprehensive review of relevant literature was conducted to analyze both the potential benefits and associated risks. While the possibility of successful pregnancy exists for MPM patients following combined CRS and HIPEC treatment, significant clinical risks during the gestational process cannot be overlooked. Current evidence remains limited, necessitating more robust clinical data to substantiate these findings.
