A case report of application of third-generation sequencing technology in preimplantation genetic testing for patients with autosomal dominant polycystic kidney disease
10.3760/cma.j.cn101441-20250425-00203
- VernacularTitle:常染色体显性遗传多囊肾病患者应用第三代测序技术进行PGT的1例报道
- Author:
Yanru LI
1
;
Huijuan ZHANG
1
;
Chenchen CUI
1
;
Baoli YIN
1
;
Cuilian ZHANG
1
Author Information
1. 河南省人民医院生殖医院 郑州大学人民医院生殖医院，郑州 450003
- Publication Type:Journal Article
- Keywords:
Third-generation sequencing;
Autosomal dominant polycystic kidney disease;
Preimplantation genetic testing
- From:
Chinese Journal of Reproduction and Contraception
2025;45(10):1054-1057
- CountryChina
- Language:Chinese
-
Abstract:
With the development of preimplantation genetic testing (PGT) technology, the application of third-generation sequencing technology in PGT has been increasing. This article reports the pregnancy outcome of a patient with autosomal dominant polycystic kidney disease who underwent PGT using the third-generation sequencing technology. It summarizes the technical characteristics of third-generation sequencing technology, as well as its significant advantages and limitations in PGT for families with de novo mutations.
