Effect of overweight/obesity on female ART outcomes and its mechanisms
10.3760/cma.j.cn101441-20250115-00019
- VernacularTitle:超重/肥胖对女性行辅助生殖助孕结局的影响及其作用机制
- Author:
Siru HOU
1
;
Shanshan WU
1
;
Siwen ZHANG
1
;
Shan GAO
1
;
Jichun TAN
1
Author Information
1. 中国医科大学附属盛京医院生殖二科,沈阳 110004
- Publication Type:Journal Article
- Keywords:
Obesity;
Reproductive techniques, assisted;
Live birth;
Pregnancy complications;
Body mass index
- From:
Chinese Journal of Reproduction and Contraception
2025;45(6):632-636
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the incidence of infertility has been steadily increasing. Obesity, recognized as a chronic inflammatory condition, can not only lead to various chronic diseases such as hypertension and diabetes, but also adversely affects female reproductive health,including rare ovulation, anovulation, menstrual irregularities, and even infertility. The reproductive outcomes of overweight/obese women are not optimistic even among people undergoing assisted reproductive technology (ART).However, the mechanisms of overweight and obesity on ART outcomes remain poorly understood. This review aims to summarize current evidence on the impact of overweight and obesity on ART outcomes in women and explore the potential mechanisms.