Application of dienogest in infertile patients with endometriosis
10.3760/cma.j.cn101441-20241018-00379
- VernacularTitle:地诺孕素在子宫内膜异位症不孕患者中的应用研究进展
- Author:
Yingxi WANG
1
;
Lina WANG
1
;
Rong LI
1
;
Xiumei ZHEN
1
Author Information
1. 北京大学第三医院生殖医学中心，北京 100191
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Infertility;
Reproductive techonology, assisted;
Dienogest
- From:
Chinese Journal of Reproduction and Contraception
2025;45(2):202-206
- CountryChina
- Language:Chinese
-
Abstract:
Compared with traditional gonadotropin-releasing hormone analogues, dienogest demonstrates several advantages, including a more favorable side effect profile, enhanced cost-effectiveness, and improved quality of life for patients. This article provides a comprehensive review of the clinical applications of dienogest in the management of endometriosis and its associated infertility. It explores the drug's mechanisms of action as a synthetic progestin, including its ability to inhibit the growth of endometriosis lesions and modulate local inflammatory responses, thereby alleviating symptoms and preserve ovarian function to enhance fertility outcomes. Future research should focus on validating the efficacy and safety of dienogest within assisted reproductive technology, ultimately providing more effective therapeutic options for individuals facing endometriosis-related infertility.
