Research progress on dual roles of pathogen recognition receptors in neurotropic virus infection
- VernacularTitle:病原体识别受体在嗜神经病毒感染中的双重作用研究进展
- Author:
Yu ZHANG
1
;
Yuantao ZHOU
1
;
Yang XIAO
1
;
Xiaoning LIU
1
;
Xiaoli HE
1
;
Lyuyan TAO
1
;
Li LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Innate immunity; Pathogen recognition receptor; Neurotropic virus; Dual roles
- From: Chinese Journal of Immunology 2025;41(5):1257-1262
- CountryChina
- Language:Chinese
- Abstract: Neurotropic viruses are a group of viruses that highly sensitive to central nervous system.As the first line of defense against pathogen invasion,the activation of pathogen recognition receptor signaling network in innate immune system plays a"double-edged"role in the process of neurotropic virus infection,which has both antiviral effect and may aggravate virus infection under certain circumstances.This article reviews the research progress on dual roles of pathogen recognition receptors in neurotropic virus infection.
