Research progress of chronic endometritis affecting embryo implantation
10.3760/cma.j.cn101441-20240420-00137
- VernacularTitle:慢性子宫内膜炎影响胚胎种植的研究进展
- Author:
Jumei SHI
1
;
Xiaoli ZHAO
1
;
Tian XIA
1
Author Information
1. 天津中医药大学第一附属医院生殖中心 国家中医针灸临床医学研究中心，天津 300193
- Publication Type:Journal Article
- Keywords:
Chronic endometritis;
Embryo implantation;
Endometrial receptivity;
Maternal-fetal communication
- From:
Chinese Journal of Reproduction and Contraception
2024;44(10):1047-1051
- CountryChina
- Language:Chinese
-
Abstract:
Chronic endometritis (CE) is an important pathological factor leading to infertility in women of childbearing age, and its characteristic manifestations are imbalanced immune-inflammatory homeostasis and abnormal microbial diversity. CE is an important factor leading to embryo implantation failure, which is closely related to the mechanism of chronic endometrial inflammation affecting follicle development, abnormal microflora mediating endometrial immune-metabolic microenvironment disorder, blocking mother-to-fetus interface signal communication, and reducing endometrial receptivity. In this paper, the characteristics of CE and its related mechanisms affecting embryo implantation were reviewed in order to provide therapeutic ideas for CE combined with embryo implantation failure.
