Clinical analysis of comprehensive surgical treatment for brucellosis with chest wall cyst as its main manifestation
10.3760/cma.j.cn231583-20231207-00127
- VernacularTitle:以胸壁囊肿为主要表现的布鲁氏菌病外科综合治疗临床分析
- Author:
Dingfeng QIAN
1
;
Dingding WU
;
Xia ZHANG
;
Shijie NIU
;
Jinzhi YANG
;
Jiang GUO
;
Kun LU
;
Shengqiang GU
Author Information
1. 中国人民解放军陆军第九四八医院心胸烧伤外科，乌苏 833000
- Publication Type:Journal Article
- Keywords:
Brucellosis;
Chest wall cyst;
Surgery;
Comprehensive treatment
- From:
Chinese Journal of Endemiology
2025;44(2):133-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the comprehensive surgical treatment of brucellosis with chest wall cysts as the main manifestation.Methods:Retrospective analysis was made on the general information epidemiological characteristics, clinical manifestations, laboratory examinations, imaging examinations, treatment and outcomes of five patients with brucellosis mainly manifested by chest wall cysts admitted to the 948 Hospital of the People's Liberation Army from July 2019 to June 2022.Results:Among the 5 patients, there were 4 males and 1 female, aged between 23 and 64 years old, with a clear history of contact with cattle and sheep. The main clinical manifestation was painless cystic masses on the chest wall. Both the serum tiger red plate agglutination test (RBPT) and the test tube agglutination test (SAT) were positive. Four cases were infected with Brucella and one case was infected with Actinobacillus pleuropneumoniae (considered as Brucella infection based on the overall condition). All patients exhibited abnormal chest wall signals (manifesting as hypointense on T1-weighted imaging and hyperintense on T2-weighted imaging) on magnetic resonance imaging(MRI), and were ultimately diagnosed with brucellosis presenting predominantly as chest wall cysts. After complete removal of the chest wall cyst through surgery, a combination treatment of rifampicin capsules and doxycycline hyclate tablets was given for 6 weeks. There were no significant adverse reactions and the wound healed in one stage. During the postoperative follow-up period of 11 - 40 months, MRI reexamination demonstrated no evidence of chest wall cyst recurrence, and all SAT results were negative. Conclusions:Patients with brucellosis presenting as chest wall cysts are clinically rare and lack specific symptoms. Surgical resection of the affected lesion combined with early, standardized, combined, and full course antimicrobial therapy results in a good prognosis for the patient.
