Advances in CRISPR-based biosensors for non-nucleic acid target detection
10.19745/j.1003-8868.2025206
- VernacularTitle:基于CRISPR的生物传感器在非核酸靶标检测中的应用综述
- Author:
Ying-xi HOU
1
;
Hao ZHANG
Author Information
1. 山东第一医科大学附属省立医院手足与显微重建外科二病区,济南 250021
- Publication Type:Journal Article
- Keywords:
clustered regularly interspaced short palindromic repeats;
biosensor;
non-nucleic acid target;
detection of non-nucleic acid target;
CRISPR/Cas system
- From:
Chinese Medical Equipment Journal
2025;46(11):91-102
- CountryChina
- Language:Chinese
-
Abstract:
The biosensors based on clustered regularly interspaced short palindromic repeats(CRISPR)were introduced in terms of detection strategies and advantages.The current situation of the CRISPR-based biosensors was reviewed when applied to detecting non-nucleic acid targets such as proteins,exosomes,small molecules,enzymes,hormones and antibodies.The deficiencies of the CRISPR-based biosensors were analyzed during the application,and the future development directions were envisioned.
