Factors associated with the occurrence of dysphagia in older adult patients with Parkinson's disease
10.3760/cma.j.cn341190-20240419-00438
- VernacularTitle:老年帕金森病患者发生吞咽困难的相关因素分析
- Author:
Yan ZHANG
1
;
Sijia JIN
1
Author Information
1. 浙江新安国际医院老年科，嘉兴 314000
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Deglutition disorders;
Risk factors;
Uric acid;
Aged;
Logistic models;
Regression analysis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2025;32(2):234-238
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the risk factors for dysphagia in older adult patients with Parkinson's disease.Methods:The clinical data of 100 older adult patients with Parkinson's disease admitted to Zhejiang Xin'an International Hospital between January 2022 and December 2023 were retrospectively analyzed. The patients were divided into two groups based on the presence of dysphagia: an occurrence group ( n = 40) and a non-occurrence group ( n = 60). General data and clinical characteristics of both groups were compared. Multivariate logistic regression analysis was performed to analyze the risk factors associated with the occurrence of dysphagia in older adult patients with Parkinson's disease. Results:In the cohort of 100 patients, the percentages of those aged 70 years and above, those with a Parkinson's disease H-Y classification greater than 3, those with an Eating Assessment Tool-10 (EAT-10) score of 3 or higher, and the Unified Parkinson's Disease Rating Scale (UPDRS) score in the occurrence group were 75.00% (30/40), 75.00% (30/40), 80.00% (32/40), and (17.23 ± 1.02), respectively. These measurements were higher than those in the non-occurrence group [16.67% (28/60), 43.33% (26/60), 33.33% (20/60), (13.23 ± 0.48), χ2 = 7.91, 9.77, 20.94, t = 22.44, P < 0.05]. The level of uric acid in the occurrence group was significantly lower than that in the non-occurrence group [(345.63 ± 11.35) μmol/L vs. (375.62 ± 10.24) μmol/L, t = 12.41, P < 0.05]. The results of the multivariate logistic regression analysis indicated that age of 70 years and older, H-Y classification greater than 3, Eating Assessment Tool-10 score of 3 or higher, Unified Parkinson's Disease Rating Scale score, and uric acid level were relevant risk factors for dysphagia in older adult patients with Parkinson's disease ( OR = 3.44, 3.82, 3.86, 3.60, 3.71, all P < 0.05). Conclusions:Age of 70 years and older, H-Y classification greater than 3, Eating Assessment Tool-10 score of 3 or higher, Unified Parkinson's Disease Rating Scale score, and uric acid level are relevant risk factors for dysphagia in older adult patients with Parkinson's disease.
