Meta-analysis of the incidence of sarcopenia and risk factors in patients with chronic heart failure
10.3760/cma.j.cn211501-20240616-01550
- VernacularTitle:慢性心力衰竭患者肌少症发生率及危险因素的Meta分析
- Author:
Fengfeng HAN
1
;
Yanping ZHAI
;
Mengwei LI
;
Yonghui WU
;
Jiajia XU
Author Information
1. 山西中医药大学护理学院,晋中 030619
- Publication Type:Journal Article
- Keywords:
Heart failure;
Sarcopenia;
Risk factor;
Meta-analysis
- From:
Chinese Journal of Practical Nursing
2024;40(35):2736-2742
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the risk factors of sarcopenia in patients with chronic heart failure, and to provide a basis for delaying the occurrence of sarcopenia and preventing the adverse outcome of sarcopenia.Methods:Cross-sectional studies, cohort studies and case-control studies of sarcopenia in PubMed, Cochrane Library, Web of Science, EMBase, China National Knowledge Infrastructure, China biomedical database (Sinomed), VIP database, Wanfang medical database were searched from database establishment to November 30, 2023. Meta-analysis was performed using RevMan 5.4 and Stata18.0 software.Results:In total, 16 articles were included, including 11 risk factors. The results showed that the incidence of chronic heart failure was 31.00%. The age of sarcopenia in chronic heart failure ( OR = 1.09, 95% CI 1.06-1.11), other chronic diseases ( OR = 6.57, 95% CI 3.29-13.10), cardiac function grade ( OR = 3.24, 95% CI 1.48-7.08), left ventricular ejection fraction ( OR = 0.96, 95% CI 0.94-0.97). Conclusions:Advancedage, comorbididy with other chronic diseases, and high cardiac function class are the risk factors for the development of sarcopenia in patients with chronic heart failure, and high left ventricular ejection fraction is a protective factor. Medical staff should screen early, identify high-risk groups early, strengthen health education, and give targeted interventions to slow down the development of sarcopenia to improve the quality of life of patients.