Research progress on the mechanism of quercetin in preventing and treating acute lung injury
10.12092/j.issn.1009-2501.2025.09.014
- VernacularTitle:槲皮素防治急性肺损伤作用机制的研究进展
- Author:
Yiyan LIN
1
;
Yueying WU
;
Rui YAN
;
Dong WU
Author Information
1. 广东医科大学附属医院呼吸与危重症医学科,湛江 524000,广东;广东医科大学第一临床医学院,湛江 524000,广东
- Publication Type:Journal Article
- Keywords:
quercetin;
acute lung injury;
anti-in-flammatory;
anti-oxidant stress;
ferroptosis
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(9):1272-1280
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury is an acute and criti-cal respiratory disease with complex pathogenesis,which has a high incidence rate and high mortality.At present,acute lung injury is mainly treated by mechanical ventilation,glucocorticoid anti-inflam-matory and extracorporeal membrane oxygen-ation.Traditional Chinese medicine also shows great potential in improving the clinical manifesta-tions and prognosis of patients.Quercetin is a fla-vonol compound,which can prevent and treat acute lung injury by anti-inflammatory,anti-oxida-tive stress,regulating programmed cell death,anti-bacterial and antiviral.This article summarizes the mechanism of action and research progress of quercetin in the treatment of acute lung injury,aiming to provide reference for subsequent re-search and clinical applications.
