Research progress on the addictivity and neurotoxicity of ketamine
10.12092/j.issn.1009-2501.2025.09.010
- VernacularTitle:氯胺酮成瘾性和神经毒性研究进展
- Author:
Zhian ZI
1
;
Tingyi ZHAO
;
Gongwu WANG
;
Jun CAO
Author Information
1. 云南师范大学生命科学学院,昆明 650500,云南
- Publication Type:Journal Article
- Keywords:
ketamine;
addictivity;
neurotoxicity
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(9):1233-1242
- CountryChina
- Language:Chinese
-
Abstract:
As a new type of rapid antidepres-sant,ketamine has provided a new approach for the treatment and research on the pathological mechanism of major depressive disorder.However,the addictive potential and neurotoxicity of ket-amine have become issues that cannot be ignored in clinical medication.This article briefly introduces the relevant research progress on ketamine addic-tion and neurotoxicity mechanisms at home and abroad,hoping to provide a reference for the ratio-nal development and utilization of ketamine.
