Advances in animal models of diabetic erectile dysfunction based on therapeutic approaches
10.12092/j.issn.1009-2501.2025.09.009
- VernacularTitle:基于治疗方法的糖尿病勃起功能障碍动物模型研究进展
- Author:
Jiawen JING
1
;
Qingbo MENG
;
Zheng BI
;
Fanjing WANG
;
Yufan LI
;
Zhaohui FANG
Author Information
1. 安徽中医药大学第一临床医学院,合肥 230038,安徽
- Publication Type:Journal Article
- Keywords:
diabetic erectile dysfunction;
animal models;
research progress;
therapeutic approaches
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(9):1224-1232
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic erectile dysfunction is a com-mon complication of diabetes that severely affects the quality of life of men and their sexual partners.Active participation in scientific research on diabet-ic erectile dysfunction is particularly important,and animal models are an important basis for exploring the pathogenesis of the disease,evaluating the effi-cacy of drug treatments,and developing new drugs.The pathogenesis of diabetic erectile dys-function is complex,and current treatments mainly focus on regulating blood sugar,anti-oxidative stress,PDE5 inhibitors,stem cell therapy,inhibiting neurovascular injury,anti-fibrosis,traditional Chi-nese medicine,and other aspects.In particular,cor-recting hyperglycemia is crucial for preventing or stopping the progression of the disease.This article summarizes and updates existing treatment meth-ods by reviewing the latest literature,and reviews the animal models used in different treatment methods,in order to provide a reference for animal experiments and clinical treatment.
