Research progress on epigenetic regulation mechanism of oral adenoid cystic carcinoma
10.11904/j.issn.1002-3070.2025.05.012
- VernacularTitle:口腔腺样囊性癌的表观遗传学调控机制研究进展
- Author:
Qing ZHOU
1
;
Yamei WANG
Author Information
1. 首都医科大学基础医学院(北京 100069)
- Publication Type:Journal Article
- Keywords:
oral adenoid cystic carcinoma;
epigenetics;
regulatory mechanisms
- From:
Practical Oncology Journal
2025;39(5):437-444
- CountryChina
- Language:Chinese
-
Abstract:
Oral adenoid cystic carcinoma(OACC)is one of the malignant tumors from the oral cavity,with strong invasion and infiltration ability,and poor prognosis for patients.Studies have shown that epigenetic mechanisms such as DNA methylation,histone modification,non-coding RNAs,and chromatin remodeling are involved in regulating the occurrence,development,invasion,and me-tastasis of OACC.The in-depth research of epigenetic regulatory mechanisms has important clinical significance for the prevention,di-agnosis,and targeted therapy of OACC.This article reviews the epigenetic regulatory mechanisms and new advances in therapeutic re-search of OACC.
