Research progress of phytochemicals in tumor immunotherapy

VernacularTitle:植物化学物在肿瘤免疫治疗中的研究进展
Author: Xuan ZHANG ¹ ; Juan LI ; Chuanfeng FANG ; Hong TIAN ; Jiaren LIU
Author Information

1. 哈尔滨医科大学附属第四医院检验科(哈尔滨 150001)
Publication Type:Journal Article
Keywords: phytochemicals; tumor; immunotherapy
From: Practical Oncology Journal 2025;39(5):428-432
CountryChina
Language:Chinese
Abstract: In recent years,the incidence and mortality of malignant tumors have been increasing year by year,becoming a se-rious challenge to global public health.Unlike traditional treatment methods,tumor immunotherapy activates the body's own immune system to against tumors,and has significant advantage such as minimal side effects,long-lasting efficacy,and strong targeting.Howev-er,immunotherapy also has issues such as frequent adverse reactions and high treatment costs.In order to enhance the efficacy of im-munotherapy,some phytochemicals are used in the field of immunotherapy as modulators.These phytochemicals not only increase the sensitivity of tumor cells to immune cells,but also reduce the expression of immune checkpoint proteins.Therefore,this article provides a review of phytochemicals that play an important role in tumor immunotherapy and their related mechanisms of action.