Analysis of gastroscopic screening and follow-up results among high-risk populations for gastric cancer in Gejiu City,Yun-nan Province
10.11904/j.issn.1002-3070.2025.05.007
- VernacularTitle:云南省个旧市胃癌高危人群的筛查与随访结果分析
- Author:
Yun LI
1
;
Pinghui SHI
1
Author Information
1. 昆明医科大学第五附属医院消化内科(个旧 661000)
- Publication Type:Journal Article
- Keywords:
gastric cancer;
high-risk population;
gastroscopic screening;
helicobacter pylori;
Gejiu City
- From:
Practical Oncology Journal
2025;39(5):405-411
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of this study was to analyze the gastroscopic screening results of high-risk populations for gastric cancer in Gejiu City from 2021 to 2023,and to provide theoretical basis for gastric cancer prevention and treatment in this city.Methods A questionnaire survey was conducted to assess the risk of gastric cancer among residents aged 40 and above in Gejiu City.Gastroscopy and pathological biopsy were performed on those assessed as high-risk for gastric cancer,and the screening results were statistically analyzed.Results From 2021 to 2023,a total of 24,391 residents were evaluated,of which 7,978 were at high-risk of gastric cancer.Among them,2,473 individuals completed gastroscopy and pathological examination,with a screening rate of 31.00％.Twenty-eight cases of gastric cancer were detected,and the detection rate of gastric cancer in high-risk populations was 1.13％;Among them,there were 9 cases of early-stage gastric cancer,with an early diagnosis rate of 46.43％.The overall infection rate of Helicobacter pylori(HP)was 62.00％,and it increased significantly with the severity of gastric mucosal lesions(P＜0.001).The detection rates of gastric cancer and precancerous lesions were significantly higher in males,ethnic minorities,and HP-infected individuals was higher than those in females,Han people,and non-HP-infected individuals,and the differences were statistically sig-nificant(P＜0.05).Following-up results showed that 1 case(2.08％)of severe atrophic gastritis progressed to early gastric cancer,and 2 cases(6.67％)of low-grade intraepithelial neoplasia progressed to early gastric cancer.Conclusion The detection rate of gas-tric cancer among high-risk populations in Gejiu City was relatively high,however the proportion of early-stage cases remained low,indicating that the rate of early diagnosis still needs to be improved.Males,ethnic minorities,and HP-infected individuals are key tar-get groups for gastric cancer prevention and control in this region.HP infection may be closely related to the progression of gastric mu-cosal lesions and the occurrence of gastric cancer,and relevant interventions should be strengthened.
