Differentiating bronchiolar adenoma from minimally invasive adenocarcinoma based on high-resolution CT features
10.3969/j.issn.1002-1671.2025.10.009
- VernacularTitle:基于高分辨率CT特征鉴别细支气管腺瘤与微浸润性肺腺癌
- Author:
Ziqian ZHAO
1
;
Dan HAN
;
Haiyan YANG
;
Tengfei KE
;
Wenyan WEI
;
Yan WU
;
Ying TAO
;
Xinhui YANG
;
Fengyi LI
;
Wen ZHAO
Author Information
1. 昆明医科大学第一附属医院影像科,云南 昆明 650032
- Publication Type:Journal Article
- Keywords:
bronchiolar adenoma;
minimally invasive adenocarcinoma;
computed tomography
- From:
Journal of Practical Radiology
2025;41(10):1633-1638
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pathological features of bronchiolar adenoma(BA)and its specific high-resolution computed tomography(HRCT)signs,and to differentiate BA from minimally invasive adenocarcinoma(MIA)using a non-invasive preoperative method.Methods A total of 80 patients with BA and 130 patients with MIA were retrospectively selected,and the clinical information and HRCT features were compared.All cases were divided into development set and test set at a 7︰3 ratio.Logistic regression analysis was used to screen the independent predictors of MIA and construct a model.Results There were significant differences in age,lobe distribution,density,vacuole sign,tumor-related vessels number(TVN),and distance to pleura(DTP)between BA and MIA patients(P<0.05).Age,density,TVN,DTP and long diameter were identified as independent predictors of MIA.A model was constructed,with area under the curve(AUC)of 0.887 and 0.884 in the development and test sets,respectively.Conclusion The model based on HRCT morphological features of BA and MIA demonstrates superior diagnostic performance compared to individual CT morphological features.
